On 31 December 2023, the Guidelines for governance settings, were published to familiarise STEM start-ups with the topic of responsibility and to promote the adoption and application of the SRSM – Social Responsibility for Start-ups Model, with its 24 qualitative indicators and 7 worksheets. The Guidelines, drafted by the K&I team in the context of the European RRIStart project, were the subject of a consultation with the project partners and some stakeholders of the ‘quadruple helix’. They were also tested by a group of STEM Start-ups. The latter found the Guidelines a clear and useful tool to start a process of reflection, decision-making and implementation of activities based on a responsible approach to business creation and the definition of a new product or service.