On 5th Novembre 2021 Claudia Colonnello (K&I) visited the Aretaeio Hospital in Nikosia and attended a meeting with the CEO of the Hospital (Michalis Papadopoulos) and the Aretaeio’s team in CHERRIES (Stelios Yiallouros and Katerina Georgiou). The meeting was aimed at a reflection on the on-going RRI-demand driven territorial experimentation and on the potential for an institutional change pathway stemming from the CHERRIES experience, related to the idea to establish a regional multi-actor Centre of reference for responsible innovation in health within the Hospital.